Craig Melvin found himself at the centre of a playful GLP-1 conversation on Today after cohost Dylan Dreyer asked him whether he was using a weight-loss injection.
The exchange happened during the September 24, 2026, episode of the show’s third hour. The hosts had been discussing how fast-food restaurants are adapting to customers who use GLP-1 medications.
Dreyer later revealed that she had asked Melvin off-camera whether he was taking “the shot”. Melvin joked that he interpreted the question differently.
The conversation also led Melvin to confirm that he has lost some weight recently. However, he did not say whether a GLP-1 medication was responsible.
Dylan Dreyer Asked Craig Melvin About a GLP-1
The conversation came up after the show’s discussion about GLP-1 medications and changing eating habits.
According to People, Al Roker brought up Dreyer’s earlier question when the cameras returned to the hosts. Dreyer explained that she had simply asked Melvin whether he was taking the injection.
She also clarified that she was not trying to judge her long-time colleague. Instead, she said she was asking because she knows many people who use GLP-1 medications.
Melvin responded humorously, saying he took the question to mean that Dreyer thought he should be using the medication.
The exchange remained light-hearted as the two hosts joked about whether Dreyer’s question had been judgemental.
Craig Melvin Confirms He Has Lost Weight
Al Roker then pointed out that Melvin appeared to have lost weight.
Melvin acknowledged the change and confirmed that he had, in fact, lost some weight.
That statement, however, did not answer the central question about GLP-1 medication.
Melvin did not publicly confirm or deny using a GLP-1 during the segment. Recent coverage from People and other outlets likewise reported that the Today hosts have not publicly confirmed that they use these medications.
Therefore, his recent weight loss should not be presented as evidence that he is taking Ozempic, Wegovy, Mounjaro, Zepbound or another GLP-1 drug.
Why GLP-1 Drugs Are Part of the Conversation
GLP-1 medications have become a major topic in conversations about diabetes treatment and weight management.
Some medications in this category are approved for type 2 diabetes, while others have specific approvals for chronic weight management. For example, the FDA approved tirzepatide under the brand name Zepbound for chronic weight management in certain adults with obesity or overweight and a related health condition. Tirzepatide is also marketed as Mounjaro for type 2 diabetes.
Semaglutide is another medication associated with brands including Ozempic and Wegovy. In March 2026, the FDA approved a higher-dose version of Wegovy for certain adults with obesity or overweight and a weight-related condition.
Because these medications have become increasingly visible in popular culture, celebrities and television personalities are frequently asked about whether they use them.
Other Today Personalities Have Discussed GLP-1s
Craig Melvin’s exchange comes amid broader conversations about weight-loss medications among television personalities.
In September 2025, Jenna Bush Hager discussed her decision not to use a GLP-1 during Today with Jenna & Friends. She said her love of food was one reason she had not pursued the medication, while also mentioning other reasons.
Her comments illustrate how differently public figures have approached the growing popularity of GLP-1 medications. Some have publicly discussed using them, while others have explained why they have chosen not to.
Still, those individual experiences should not be treated as medical advice. The FDA has also warned about the risks associated with unapproved versions of GLP-1 drugs and advises patients to discuss prescription medications with healthcare professionals.
What, Craig Melvin? Actually Confirmed
For now, the facts from the Today exchange are straightforward:
- Dylan Dreyer asked Craig Melvin whether he was using a GLP-1 injection.
- Melvin joked about how he interpreted her question.
- Al Roker noted Melvin’s recent weight loss.
- Melvin confirmed that he had lost some weight.
- Melvin did not say whether he uses a GLP-1 medication.
So, while the conversation sparked speculation, there is no confirmation from Melvin in this segment that a GLP-1 medication contributed to his weight loss.
The moment ultimately became another humorous exchange between long-time colleagues, with Roker jokingly comparing their playful disagreement to a family argument.